Opsumit: Uses – Side Effects – Warnings

Opsumit is a medication used to treat pulmonary arterial hypertension (PAH). PAH is a type of high blood pressure that affects the arteries in the lungs and the right side of the heart. This medication works by relaxing the blood vessels in the lungs, making it easier for the heart to pump blood through them.

In this article, we will discuss the uses, benefits, side effects, and warnings of Opsumit.

Uses

Opsumit is used to treat pulmonary arterial hypertension (PAH) in adults. It is classified as an endothelin receptor antagonist (ERA) medication. Endothelin is a hormone that constricts the blood vessels in the lungs and raises blood pressure. By blocking the effects of endothelin, Opsumit helps to relax the blood vessels in the lungs, making it easier for blood to flow through them.

Opsumit can help to improve exercise ability, delay disease progression, and reduce hospitalizations related to PAH.

Benefits

Opsumit has been shown to provide several benefits for people with PAH. Some of these benefits include:

1. Improved exercise ability – Opsumit can help to improve the ability to exercise and be physically active.

2. Delayed disease progression – Opsumit may help to slow down the progression of PAH, which can help to maintain lung function and prevent further damage.

3. Reduced hospitalization – Opsumit may help to reduce the need for hospitalization related to PAH, which can improve quality of life and reduce healthcare costs.

Side Effects

As with any medication, Opsumit can cause side effects. The most common side effects of Opsumit include:

1. Headache – Opsumit can cause headaches, which may be mild or severe.

2. Nausea – Opsumit can cause nausea, which may be mild or severe.

3. Diarrhea – Opsumit can cause diarrhea, which may be mild or severe.

4. Abdominal pain – Opsumit can cause abdominal pain or discomfort.

5. Flushing – Opsumit can cause a warm, red flushing of the skin.

6. Anemia – Opsumit can cause a decrease in red blood cells, which can result in anemia.

7. Elevated liver enzymes – Opsumit can cause an increase in liver enzymes, which may indicate liver damage.

8. Fluid retention – Opsumit can cause a buildup of fluid in the legs, ankles, or feet.

These side effects may go away on their own after a few days or weeks. However, if they persist or become severe, it is important to speak with a healthcare provider.

Warnings

Opsumit is not recommended for use in pregnant women, as it can harm the developing fetus. Women who are of childbearing age should use effective contraception while taking Opsumit and for a month after stopping the medication.

Opsumit can also interact with certain medications, including cyclosporine and rifampin. It is important to inform a healthcare provider of all medications, supplements, and herbal remedies being taken before starting Opsumit.

Opsumit can cause liver damage, so it is important to have regular liver function tests while taking this medication. Signs of liver damage may include yellowing of the skin or eyes, dark urine, or abdominal pain.

FAQs

What is Opsumit used for?

Opsumit is used to treat pulmonary arterial hypertension (PAH) in adults.

How does Opsumit work?

Opsumit works by blocking the effects of endothelin, a hormone that constricts blood vessels in the lungs and raises blood pressure.

What are the most common side effects of Opsumit?

The most common side effects of Opsumit include headaches, nausea, diarrhea, abdominal pain, flushing, anemia, elevated liver enzymes, and fluid retention.

Can Opsumit be used during pregnancy?

Opsumit is not recommended for use in pregnant women, as it can harm the developing fetus.

What should I do if I experience side effects while taking Opsumit?

If you experience side effects while taking Opsumit, speak with a healthcare provider. Some side effects may go away on their own, while others may require medical attention.

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