Synjardy: Uses – Side Effects – Warnings

Synjardy is a prescription medicine used to manage type 2 diabetes. It is a combination medicine that contains two active ingredients: empagliflozin and metformin. The medication helps control blood sugar levels by lowering glucose production in the liver, increasing glucose removal by the kidneys, and reducing insulin resistance.


The primary use of Synjardy is to manage type 2 diabetes. The medication is designed to help control blood sugar levels and lower the risk of complications associated with diabetes, such as heart attack, stroke, kidney damage, and blindness. The medication can be used alone, or in combination with other diabetes medications as recommended by the healthcare provider.

The medication is not intended for use in type 1 diabetes or diabetic ketoacidosis.


Synjardy provides several benefits for individuals with type 2 diabetes. It effectively controls blood sugar levels by blocking glucose production in the liver and increasing glucose excretion in the kidneys. The medication also helps reduce the risk of cardiovascular disease, one of the most common complications associated with diabetes.

Some of the benefits of Synjardy include:

  • Lowering blood sugar levels
  • Reducing insulin resistance
  • Improving glycemic control
  • Reducing the risk of cardiovascular disease
  • Improving overall health and quality of life

Side Effects

Like any medication, Synjardy can cause side effects. While the medication is generally well-tolerated, some individuals may experience the following side effects:

  • Urinary tract infections
  • Genital yeast infections
  • Dehydration
  • Dizziness
  • Nausea
  • Headache
  • Vomiting
  • Stomach pain

In rare cases, Synjardy can cause more serious side effects such as allergic reactions, kidney problems, and lactic acidosis. Patients should seek urgent medical attention if they experience symptoms such as difficulty breathing, swelling of the face, lips or tongue, severe stomach pain, or chest discomfort.


Before taking Synjardy, patients should discuss their medical history, allergies, and current medications with their healthcare provider. The medication should not be used in individuals allergic to empagliflozin or metformin, those with kidney or liver problems, or those experiencing diabetic ketoacidosis.

Patients with a history of heart disease, stroke, or blood vessel problems should use Synjardy with caution. The medication can cause dehydration, which may lead to a drop in blood pressure and fainting.

If you are pregnant or planning to become pregnant, consult your healthcare provider before taking Synjardy. The medication can pass into breast milk, and it is not recommended for breastfeeding mothers.

Lastly, Synjardy may interact with other medications, including diuretics and blood pressure medications. Patients should inform their healthcare provider of any medications they are taking before starting Synjardy.


Can Synjardy be used for type 1 diabetes?

No. Synjardy is only approved for use in type 2 diabetes.

What should I do if I miss a dose?

If you forget to take a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double your dose to make up for the missed one.

Can I drink alcohol while taking Synjardy?

While moderate alcohol consumption may be acceptable, patients should avoid excessive alcohol intake while taking Synjardy as it can increase the risk of dehydration and low blood sugar.

Does Synjardy cause weight loss?

Synjardy has been shown to help some individuals lose weight, but it is not a weight loss medication and should not be used for this purpose.

How long does Synjardy take to work?

Each patient may respond differently, but Synjardy typically starts working within a few hours after taking the medication.


In conclusion, Synjardy is a combination medication used to treat type 2 diabetes. It helps control blood sugar levels and reduces the risk of complications associated with the disease. While generally well-tolerated, patients should consult their healthcare professional before taking Synjardy to ensure it is appropriate for them. If side effects occur, patients should seek medical attention immediately.

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