Depakote ER (divalproex sodium) is a medication that is primarily used to treat seizures and bipolar disorder. This medication is available in extended-release tablets that release the medication over a longer period of time.
Uses
Depakote ER is primarily used to treat seizures and bipolar disorder. Seizures are caused by abnormal electrical activity in the brain, and Depakote ER works by increasing the levels of gamma-aminobutyric acid (GABA), a neurotransmitter that helps to reduce the activity in the brain. Bipolar disorder is a mental health disorder that causes dramatic shifts in mood, energy, and activity levels. Depakote ER is used to stabilize the mood swings associated with this disorder.
Benefits
Depakote ER can provide several benefits for individuals with seizures or bipolar disorder. These include:
- Reduced frequency and severity of seizures
- Stabilized mood and reduced risk of manic or depressive episodes
- Decreased irritability and aggression
- Improved overall quality of life
Side Effects
As with any medication, Depakote ER can cause side effects. The most common side effects include:
- Nausea and vomiting
- Dizziness
- Blurred vision
- Headache
- Tremors
- Sleepiness
- Weight gain
Less common but more serious side effects can include:
- Liver damage
- Pancreatitis
- Blood disorders
- Allergic reactions
It is important to speak with a healthcare provider if you experience any of these side effects while taking Depakote ER.
Warnings
There are several warnings associated with Depakote ER that individuals should be aware of. These include:
- Liver damage: Depakote ER can cause liver damage, particularly in individuals with a history of liver disease or alcohol abuse. It is important to have regular liver function tests while taking Depakote ER.
- Pancreatitis: Depakote ER can cause inflammation of the pancreas, which can be a serious and potentially life-threatening condition. Symptoms of pancreatitis include severe abdominal pain, nausea, and vomiting.
- Birth defects: Depakote ER can cause birth defects if taken during pregnancy. It is important for women of childbearing age to use effective birth control while taking Depakote ER.
- Drug interactions: Depakote ER can interact with several medications, including antidepressants, antipsychotics, and blood thinners. It is important to speak with a healthcare provider before taking any new medications while taking Depakote ER.
FAQs
Depakote ER can take several weeks to start working, and it may take several months to achieve the full benefits of the medication.
No, Depakote ER is not addictive and does not produce a “high” or euphoric effect.
Yes, Depakote ER can be used in children for the treatment of seizures and bipolar disorder. However, dosing and monitoring may be different than for adults.
Alcohol should be avoided while taking Depakote ER, as it can increase the risk of liver damage and other side effects.
No, Depakote ER should not be stopped suddenly as it can cause seizures and other serious withdrawal symptoms. It is important to speak with a healthcare provider before stopping Depakote ER.




