Phenergan: Uses – Side Effects – Warnings

Phenergan is a medication that contains promethazine, which belongs to a class of drugs known as antihistamines. It is used to manage nausea and vomiting caused by certain conditions such as migraines, motion sickness, or after undergoing surgery.


Phenergan is primarily used to manage different symptoms caused by various conditions such as:

  • Nausea and vomiting from chemotherapy or radiation therapy
  • Nausea or vomiting after surgery
  • Migraine headaches
  • Motion sickness
  • Allergies or allergic reactions such as hives, itching, and rashes
  • Difficulty sleeping (insomnia)


Phenergan has several benefits, including:

  • Reducing nausea and vomiting caused by various conditions.
  • Relief from allergic symptoms like itching, hives, and rashes.
  • It can help improve sleep quality.
  • Relief from migraine headache symptoms.
  • Motion sickness prevention and relief.

Side Effects

As with all medications, there are potential side effects that people taking Phenergan may experience. Although Phenergan is a generally safe drug, it can cause a range of side effects, including:

  • Drowsiness or dizziness
  • Dry mouth
  • Blurred vision
  • Constipation
  • Loss of coordination or balance
  • Increased sensitivity to sunlight
  • Difficulty concentrating or confusion
  • Restlessness
  • Skin sensitivity to sunlight
  • Coma or seizures in rare cases (when taking high doses)
  • Difficulty breathing
  • Swelling of the face, mouth, or tongue


Phenergan may not be suitable for everyone. Here are some of the warnings that you should keep in mind when taking Phenergan:

  • Phenergan may sometimes cause drowsiness, so you should avoid driving or operating machinery until you know how the medication affects you.
  • Phenergan can make you more sensitive to sunlight, so you should avoid prolonged exposure to the sun. Wear protective clothing and use sunscreen when outside.
  • Phenergan should be used with caution in older adults as it can cause side effects such as confusion and dizziness.
  • Phenergan is not recommended for use during pregnancy or breastfeeding unless it is deemed necessary by a healthcare professional.
  • If you have a history of seizures or epilepsy, it is important to inform your doctor before taking Phenergan as it can increase the risk of seizure.
  • If you have liver disease, kidney disease, or heart disease, discuss your condition with your doctor first.
  • Phenergan should not be given to children under two years of age


Can Phenergan be used to treat morning sickness?

Phenergan is not recommended for treating morning sickness. Consult your healthcare provider for other options.

Can I drive after taking Phenergan?

Phenergan may cause drowsiness or dizziness, so it is not advised to operate heavy machinery or drive until you know how the medication affects you.

Can I drink alcohol while taking Phenergan?

Alcohol may increase the sedative effects of Phenergan, so it is not recommended to consume alcohol while taking the medication.

Can I take Phenergan with other medications?

It is important to inform your doctor of all the medications you are taking, including prescription, over-the-counter, and herbal supplements, before taking Phenergan.

Is it safe to take Phenergan during pregnancy?

Phenergan is not recommended for use during pregnancy, especially in the first trimester. Always consult your healthcare provider before taking any medication during pregnancy or breastfeeding.

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