Vivotif: Uses – Side Effects – Warnings

Vivotif is a medication that is commonly prescribed to prevent typhoid fever. It contains live bacteria that stimulate the immune system to produce antibodies against the bacteria that cause typhoid. This article will provide an overview of the uses, benefits, side effects, and warnings associated with Vivotif.


Vivotif is primarily used to prevent typhoid fever, a potentially life-threatening illness caused by the bacteria Salmonella typhi. It is especially recommended for individuals who are traveling to areas where typhoid is prevalent or for those who may come into contact with contaminated food or water.

It is important to note that Vivotif does not provide immediate protection against typhoid fever. It should be taken at least one week before potential exposure to ensure optimal effectiveness.


Vivotif offers several benefits for individuals at risk of typhoid fever:

  1. Prevents Typhoid Fever: The primary benefit of Vivotif is its ability to prevent typhoid fever by stimulating the immune system to produce protective antibodies.
  1. Convenient Oral Administration: Vivotif comes in a capsule form that can be easily swallowed, making it a convenient option for travelers.
  1. Long-lasting Protection: After completing the recommended course of Vivotif, individuals can enjoy protection against typhoid fever for up to five years.
  1. Effective against Multiple Strains: Vivotif provides protection against multiple strains of Salmonella typhi, ensuring broad coverage.

Side Effects

While Vivotif is generally well-tolerated, some individuals may experience side effects. Common side effects include:

  • Headache
  • Nausea or vomiting
  • Abdominal pain
  • Diarrhea
  • Fever

These side effects are usually mild and resolve on their own. However, if they persist or worsen, it is important to consult a healthcare professional.

Severe side effects from Vivotif are rare but may include:

  • Allergic reactions
  • Severe abdominal pain
  • Bloody diarrhea
  • High fever
  • Yellowing of the skin or eyes (jaundice)

If any of these severe side effects occur, immediate medical attention should be sought.


Before taking Vivotif, it is important to consider the following warnings:

  • Allergy: Individuals with a known allergy to any component of Vivotif should not take this medication.
  • Immunocompromised individuals: Vivotif may not be suitable for individuals with weakened immune systems, as it contains live bacteria.
  • Pregnancy and breastfeeding: The safety of Vivotif during pregnancy and breastfeeding has not been established. Consult a healthcare professional for guidance.
  • Antibiotics: Certain antibiotics may interact with Vivotif, reducing its effectiveness. Inform your healthcare provider of any current medications.

It is essential to follow the recommended dosing schedule and complete the full course of Vivotif to ensure maximum protection against typhoid fever.


In conclusion, Vivotif is a valuable medication for preventing typhoid fever. It offers numerous benefits, including long-lasting protection and convenient oral administration. While side effects are generally mild, it is important to be aware of potential severe reactions. Following the recommended dosing schedule and adhering to the provided warnings will help ensure the safety and effectiveness of Vivotif.


Here are some commonly asked questions about Vivotif:

Can Vivotif be taken by children?

Yes, Vivotif can be prescribed to children aged six years and older. However, the dosage may vary based on age and weight. Consult a healthcare professional for appropriate guidance.

Is Vivotif effective against all strains of typhoid?

Vivotif provides protection against multiple strains of Salmonella typhi, but it may not cover every strain. It is still essential to practice proper hygiene and food safety measures when traveling to high-risk areas.

Can Vivotif cause typhoid fever?

No, Vivotif does not cause typhoid fever. It is a preventive measure that stimulates the immune system to produce antibodies against the bacteria responsible for typhoid.

Can I consume alcohol while taking Vivotif?

There are no known interactions between Vivotif and alcohol. However, excessive alcohol consumption may weaken the immune system, potentially reducing the effectiveness of Vivotif. It is advisable to drink alcohol in moderation, especially during the course of treatment.

How should Vivotif be stored?

Vivotif should be stored in a refrigerator at a temperature between 2-8°C (36-46°F). It should be kept away from children and pets.

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