Ingrezza: Uses – Side Effects – Warnings

Ingrezza is a brand name for valbenazine, a drug that is used to treat tardive dyskinesia (TD) in adults. TD is a condition characterized by involuntary movements of the face, mouth, and limbs, which can be caused by long-term use of certain antipsychotic medications. In this article, we will discuss the uses, benefits, side effects, and warnings associated with Ingrezza.


Ingrezza is approved by the United States Food and Drug Administration (FDA) for the treatment of tardive dyskinesia in adults. The drug works by inhibiting the reuptake of a neurotransmitter called dopamine, which is involved in the regulation of movement. By blocking the reuptake of dopamine, Ingrezza helps to reduce the involuntary movements associated with TD.


The main benefit of Ingrezza is the reduction of TD symptoms in adults who suffer from the condition. In clinical trials, patients who took Ingrezza experienced significant improvements in their TD symptoms compared to those who took a placebo. In particular, patients treated with Ingrezza showed reductions in facial, oral, and limb movements associated with TD. The drug was found to be safe and effective, with minimal side effects reported.

Side Effects

As with any medication, Ingrezza can have side effects, although not all patients experience them. The most common side effects reported by patients taking Ingrezza include:

– Sleepiness
– Dizziness
– Dry mouth
– Headache
– Diarrhea
– Fatigue

Less common but more serious side effects that have been reported with Ingrezza include:

– Abnormal heart rhythm
– Neuroleptic malignant syndrome (a life-threatening condition that can occur as a result of treatment with antipsychotic medications)
– Akathisia (a condition characterized by restlessness and a need to move)
– Parkinsonism (a set of symptoms similar to those of Parkinson’s disease)

If you experience any of these side effects, you should seek medical attention immediately.


Before taking Ingrezza, it is important to discuss your medical history and any existing health conditions with your doctor. Ingrezza should not be taken if you:

– Have a history of prolonged QT interval (a heart rhythm disorder)
– Are taking medications that prolong QT interval
– Have liver problems
– Are pregnant or breastfeeding

In addition, Ingrezza may interact with other medications, so it is important to discuss any other medications you are taking with your doctor.


1. How long does Ingrezza take to start working?

Ingrezza may take several weeks to start working. Your doctor will monitor your progress regularly and adjust your dosage as necessary.

2. Can I drink alcohol while taking Ingrezza?

It is recommended that you avoid alcohol while taking Ingrezza, as it can increase the risk of side effects such as sleepiness and dizziness.

3. Can Ingrezza be used to treat other conditions?

Ingrezza is currently only approved by the FDA for the treatment of tardive dyskinesia in adults.

4. How is Ingrezza taken?

Ingrezza is taken as a capsule by mouth, usually once a day.

5. Is Ingrezza addictive?

Ingrezza is not known to be addictive, but it is important to take it as directed by your doctor and to follow any dosage adjustments carefully.

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