Xospata: Uses – Side Effects – Warnings

Xospata (generic name: gilteritinib) is a prescription medication used for the treatment of acute myeloid leukemia (AML) in adult patients who have a specific genetic mutation called FLT3. The medication works by specifically targeting the FLT3 gene mutation, which is present in about 25% of patients with AML.

Uses of Xospata

Xospata is used to treat relapsed or refractory AML with a FLT3 mutation. The medication helps to stop the production of cancer cells and, in some cases, induces the death of these cells. Xospata is approved for the oral treatment of adult patients who have either relapsed or refractory FLT3-mutated AML.

Benefits of Xospata

Xospata has been shown to improve the overall survival rate in patients with FLT3-mutated AML. Studies have shown that treatment with Xospata resulted in a significantly longer median overall survival compared to standard chemotherapy. The medication has also been found to reduce the risk of relapse or death when compared to other chemotherapies.

Side Effects of Xospata

Like most medications, Xospata can have side effects. Some of the common side effects of Xospata include:

  • Fever
  • Fatigue
  • Low platelet count
  • Nausea
  • Diarrhea
  • Increased liver function tests
  • Cough
  • Rash

These side effects can vary in severity and can be managed with proper medical care.

Warnings About Xospata

Xospata should not be used by patients who are allergic to gilteritinib or any of the other inactive ingredients present in the medication. Xospata may also interact with other medications, so it is important to inform your healthcare provider about any other medications you are taking before beginning treatment with Xospata.

It is important to note that Xospata can cause serious side effects, including liver toxicity, which can be fatal. Patients should be monitored for these serious side effects and signs of liver problems, such as yellowing of the eyes or skin, abdominal pain, or dark urine. Patients should also avoid taking Xospata during pregnancy as it may harm the unborn child.

FAQs about Xospata

Q: How is Xospata administered?

A: Xospata is an oral medication that can be taken with or without food.

Q: Can Xospata be used to treat all types of AML?

A: No. Xospata is specifically indicated for the treatment of relapsed or refractory AML with a FLT3 mutation.

Q: How long does it take for Xospata to work?

A: The time it takes for Xospata to work varies from patient to patient. Your healthcare provider will monitor your progress during treatment to determine if the medication is effective.

Q: What should I do if I miss a dose of Xospata?

A: If you miss a dose of Xospata, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Q: Does Xospata have any long-term effects?

A: The long-term effects of Xospata are not yet fully known. Your healthcare provider will monitor your progress during treatment to ensure that the medication is safe and effective for you.

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